Antiplasmodial Compounds from Indonesian Marine Sponge, Xestospongia sp, against Plasmodium falciparum 3D7

Murtihapsari, Dikdik Kurnia, Tati Herlina, Dewa gede Katja, Kadarusman, Khalijah Awang, Yoshihito Shiono, and Unang Supratman

dc.contributor.author	Murtihapsari, Dikdik Kurnia, Tati Herlina, Dewa gede Katja, Kadarusman, Khalijah Awang, Yoshihito Shiono, and Unang Supratman
dc.date.accessioned	2023-02-13T14:06:11Z
dc.date.available	2023-02-13T14:06:11Z
dc.date.issued	2019-10-25
dc.identifier.issn	2548-3013
dc.identifier.uri	http://repository.unipa.ac.id:8080/xmlui/handle/123456789/1076
dc.description.abstract	A part of our continuing search for antiplasmodial compounds from Indonesian marine sponge, two steroidal alkaloids, epoxysarcovagenine-D (1) and epoxyepapakistamine-A (2), have been isolated from the ethyl acetate extract of the Indonesian marine ponge, Xestospongia sp. Their structures were identified on the basis of spectroscopic data analysis and by comparison with published spectroscopic and physicochemical properties data. Compounds 1 and 2 were isolated first time from marine sponge, Xestospongia sp., and showed strongest plasmodial activity against Plasmodium falciparum 3D7 strain with IC50 values of 0.013 and 0.158 μM, respectively	en_US
dc.publisher	Chiang Mai University	en_US
dc.relation.ispartofseries	4;1
dc.subject	Steroidal alkaloid, Xestospongia sp, Petrosiidae, Antiplasmodial activity	en_US
dc.title	Antiplasmodial Compounds from Indonesian Marine Sponge, Xestospongia sp, against Plasmodium falciparum 3D7	en_US
dc.type	Article	en_US